Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: Identification of an efficient lead for potent inhibitors of GABA transports-Reference-Cited by-同舟云学术

Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: Identification of an efficient lead for potent inhibitors of GABA transports

Published:2013-09 Issue:17 Volume:21 Page:4938-4950
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Nakada Kazuaki,Yoshikawa Mamie,Ide Soichiro,Suemasa Akihiro,Kawamura Shuhei,Kobayashi Takaaki,Masuda Eiji,Ito Yoshihiko,Hayakawa Wataru,Katayama Takahiro,Yamada Shizuo,Arisawa Mitsuhiro,Minami Masabumi,Shuto Satoshi

Funder

Grant-in-Aids for Scientific Research

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference46 articles.

1. Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication

2. Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition

3. From the Selective Serotonin Transporter Inhibitor Citalopram to the Selective Norepinephrine Transporter Inhibitor Talopram: Synthesis and Structure−Activity Relationship Studies

4. The GABA Transporter and its Inhibitors

5. GABA transporters as drug targets for modulation of GABAergic activity

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