A stereochemical journey around spirocyclic glutamic acid analogs-Reference-Cited by-同舟云学术

A stereochemical journey around spirocyclic glutamic acid analogs

Published:2022 Issue:15 Volume:20 Page:3183-3200
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Chernykh Anton V.¹²,Chernykh Alla V.¹,Radchenko Dmytro S.¹²,Chheda Pratik Rajesh³,Rusanov Eduard B.⁴,Grygorenko Oleksandr O.¹²,Spies M. Ashley³⁵,Volochnyuk Dmitriy M.¹²⁴,Komarov Igor V.¹²^ORCID

Affiliation:

1. Enamine Ltd, Chervonotkatska Street 78, Kyiv 02094, Ukraine

2. Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine

3. Division of Medicinal and Natural Products Chemistry, Department of Pharmaceutics and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City 52246, Iowa, USA

4. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska Street 5, Kyiv 02660, Ukraine

5. Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City 52246, Iowa, USA

Abstract

A practical divergent synthetic approach is reported for the library of regio- and stereoisomers of glutamic acid analogs built on the spiro[3.3]heptane scaffold.

Funder

Enamine

National Institutes of Health

Ministry of Education and Science of Ukraine

National Academy of Sciences of Ukraine

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00146B

Reference50 articles.