Diastereoselective construction of structurally diverse 2,3-dihydroquinolin-4-one scaffolds via redox neutral cascade [1,7]-hydride transfer/cyclization-Reference-Cited by-同舟云学术

Diastereoselective construction of structurally diverse 2,3-dihydroquinolin-4-one scaffolds via redox neutral cascade [1,7]-hydride transfer/cyclization

Published:2022 Issue:3 Volume:9 Page:660-666
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xie Ronghao¹,Chen Shixiao²,Xiang Xianping³,Yin Xiangcong⁴,Xu Lubin¹,Li Shuai-Shuai¹^ORCID,Wang Liang¹^ORCID,Dong Fengying¹

Affiliation:

1. College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Changcheng Rd. #700, Qingdao, 266109, P. R. China

2. Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Yushan Rd. #5, Qingdao, 266003, P. R. China

3. Peking University science park, No. 127, North Street of Zhongguancun, Beijing, 100080, P. R. China

4. Hematology Diagnosis Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, 266003, P. R. China

Abstract

The 2,3-dihydroquinolin-4-one scaffolds were constructed diastereoselectively via cascade Knoevengel condensation/[1,7]-HT/cyclization/transesterification featuring novel structures and diastereoselective construction of all-carbon quaternary centers.

Funder

National Natural Science Foundation of China

Key Technology Research and Development Program of Shandong

Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01530C

Reference42 articles.

1. Synthesis of 2-ferrocenylquinoline derivatives and evaluation of their antimalarial activity