Aromatization-driven cascade [1,5]-hydride transfer/cyclization for synthesis of spirochromanes-Reference-Cited by-同舟云学术

Aromatization-driven cascade [1,5]-hydride transfer/cyclization for synthesis of spirochromanes

Published:2023 Issue:7 Volume:10 Page:1796-1802
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Cao Lianyi¹²,Hu Fangzhi¹³^ORCID,Dong Jiacheng³,Zhang Xiao-Mei¹^ORCID,Li Shuai-Shuai¹³^ORCID

Affiliation:

1. Asymmetric Synthesis and Chiraltechnology Key Laboratory of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, China

2. University of Chinese Academy of Sciences, Beijing, China

3. College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, China

Abstract

An aromatization-driven hydride transfer-involved α-C(sp3)–H bond functionalization of the oxygen atom was developed. Easily prepared p-quinone methides were applied to initiate [1,5]-hydride transfer/cyclization for generating spirochromanes.

Funder

Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China

Xihua University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00035D

Reference61 articles.

1. Recommendations for the Evaluation of Aromatic Stabilization Energies