A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

Author:

Oliveira Marta12343,Reis Filipa S.56789,Sousa Diana567,Tavares Catarina567,Lima Raquel T.567103,Ferreira Isabel C. F. R.89111213,Santos Tiago dos567,Vasconcelos M. Helena141516175

Affiliation:

1. Institute of Biomedical Sciences Abel Salazar (ICBAS)

2. University of Porto

3. Porto, Portugal

4. Faculty of Sciences of the University of Porto (FCUP)

5. Cancer Drug Resistance Group

6. Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP)

7. 4200-465 Porto, Portugal

8. Mountain Research Centre (CIMO)

9. ESA

10. Centre of Medicinal Chemistry of the University of Porto (CEQUIMED-UP)

11. Polytechnic Institute of Bragança

12. Campus de Santa Apolónia

13. 5301-855 Bragança, Portugal

14. Laboratory of Microbiology

15. Department of Biological Sciences

16. Faculty of Pharmacy of the University of Porto (FFUP)

17. Portugal

Abstract

The G. lucidum methanolic extract inhibited the growth of a gastric cancer cell line (AGS) by interfering with cellular autophagy and cell cycle.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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