Enhancing solubility and stability of sorafenib through cyclodextrin-based inclusion complexation: <i>in silico</i> and <i>in vitro</i> studies-Reference-Cited by-同舟云学术

Enhancing solubility and stability of sorafenib through cyclodextrin-based inclusion complexation: in silico and in vitro studies

Published:2023 Issue:39 Volume:13 Page:27244-27254
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Aman Aamir¹,Ali Saba²,Mahalapbutr Panupong³,Krusong Kuakarun²,Wolschann Peter⁴^ORCID,Rungrotmongkol Thanyada¹²^ORCID

Affiliation:

1. Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand

2. Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand

3. Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand

4. Institute of Theoretical Chemistry, University of Vienna, 1090 Vienna, Austria

Abstract

Amongst all inclusion complexes of SOR with CDs, SBEβCD exhibit the highest tendency to encapsulate SOR.

Funder

Chulalongkorn University

Khon Kaen University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA03867J

Reference64 articles.

1. Nanoassemblies Based on Supramolecular Complexes of Nonionic Amphiphilic Cyclodextrin and Sorafenib as Effective Weapons to Kill Human HCC Cells

2. BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

3. Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma

4. The discovery and development of sorafenib for the treatment of thyroid cancer

5. Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat

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