Protein dynamics promote hydride tunnelling in substrate oxidation by aryl-alcohol oxidase

Author:

Carro Juan12345ORCID,Martínez-Júlvez Marta6785ORCID,Medina Milagros6785ORCID,Martínez Angel T.12345ORCID,Ferreira Patricia6785ORCID

Affiliation:

1. Centro de Investigaciones Biológicas

2. CSIC

3. Ramiro de Maeztu 9

4. Madrid

5. Spain

6. Department of Biochemistry and Molecular and Cellular Biology and Institute for Biocomputation and Physics of Complex Systems

7. University of Zaragoza

8. Zaragoza

Abstract

Kinetic and crystallograhic data define the involvement of protein motions in hydride tunnelling for substrate oxidation by aryl-alchohol oxidase.

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Reference41 articles.

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2. Fungal aryl-alcohol oxidase: a peroxide-producing flavoenzyme involved in lignin degradation

3. The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes

4. A survey of genes encoding H2O2-producing GMC oxidoreductases in 10 Polyporales genomes

5. J. Carro , A.Serrano, P.Ferreira and A. T.Martínez, in Microbial Enzymes in Bioconversions of Biomass, ed. V. K. Gupta and M. G. Tuohy, Springer, Berlin, Germany, 2016, pp. 301–322

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