An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles-Reference-Cited by-同舟云学术

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles

Published:2018 Issue:22 Volume:10 Page:10609-10619
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Hall Stephen C. L.¹²³⁴⁵^ORCID,Tognoloni Cecilia⁶⁷⁸⁴,Charlton Jack¹²³⁴,Bragginton Éilís C.⁹¹⁰¹¹¹²⁴,Rothnie Alice J.¹³¹⁴¹⁵⁴,Sridhar Pooja¹²³⁴,Wheatley Mark¹²³⁴¹⁶^ORCID,Knowles Timothy J.¹²³⁴,Arnold Thomas⁵¹⁷¹⁸⁴⁶^ORCID,Edler Karen J.⁶⁷⁸⁴^ORCID,Dafforn Tim R.¹²³⁴

Affiliation:

1. School of Biosciences

2. University of Birmingham

3. Birmingham

4. UK

5. Diamond Light Source

6. Department of Chemistry

7. University of Bath

8. Bath

9. School of Cellular and Molecular Medicine

10. University of Bristol

11. University Walk

12. Bristol

13. School of Life & Health Sciences

14. Aston University

15. Birmingham B4 7ET

16. Centre of Membrane and Protein and Receptors (COMPARE)

17. Harwell Science and Innovation Campus

18. Didcot

Abstract

Positively charged poly(styrene-co-maleimide) extracts functional membrane proteins into nanodiscs, overcoming some limitations of current nanodisc technology.

Funder

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Science and Technology Facilities Council

University of Bath

Medical Research Council

AstraZeneca

University of Bristol

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science