Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Author:

Fan Zhijin12ORCID,Jiang Cheng34ORCID,Wang Yichao5,Wang Kaiyuan6ORCID,Marsh Jade4,Zhang Da7ORCID,Chen Xin8,Nie Liming21ORCID

Affiliation:

1. School of Medicine, South China University of Technology, Guangzhou 510006, P. R. China

2. Research Center of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, P. R. China

3. School of Life and Health Sciences, The Chinese University of Hong Kong, Shenzhen 518172, China

4. Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK

5. Department of Clinical Laboratory Medicine, Tai Zhou Central Hospital (Taizhou University Hospital), Taizhou 318000, P. R. China

6. Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China

7. The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China

8. School of Chemical Engineering and Technology, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, Xi’an Jiao Tong University, Xi’an 710049, P. R. China

Abstract

Engineered EVs containing an intelligent core have been designed to interact with a living host environment and function in an ideal situation. This review provides a new insight into design of next-generation EV-based theranostic platforms.

Funder

National Natural Science Foundation of China

Zhejiang Province Public Welfare Technology Application Research Project

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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