Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 release-Reference-Cited by-同舟云学术

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Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 release

Published:2021 Issue:21 Volume:12 Page:10714-10727
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Zhi-Hong¹²,Yang Hong-Xu¹²,Jin Quan¹²,Wu Yan-Ling¹²,Cui Zhen-Yu¹²,Shang Yue¹²,Liu Jian¹²,Zhan Zi-Ying¹²,Lian Li-Hua¹²,Nan Ji-Xing¹²^ORCID

Affiliation:

1. Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China

2. Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China

Abstract

Luteolin reverses septic hepatic injury, especially inflammation, likely by regulating the release of HMGB1 through the P2X7R–RAGE–TLR4 axis.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO01746B

Reference53 articles.

1. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against Decapentaplegic, and CCAAT/Enhancer‐Binding Protein C/EBP Transcription Factors

2. Serum amyloid A promotes LPS clearance and suppresses LPS ‐induced inflammation and tissue injury

3. Intracellular Lipopolysaccharide Sensing as a Potential Therapeutic Target for Sepsis

4. HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression

5. The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

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3. Luteolin attenuates CCl4-induced hepatic injury by inhibiting ferroptosis via SLC7A11;BMC Complementary Medicine and Therapies;2024-05-16

4. Luteolin: A promising multifunctional natural flavonoid for human diseases;Phytotherapy Research;2024-04-26

5. Research Progress in the Relationship Between P2X7 and Flavonoids in Cardiovascular Disease;Acta Poloniae Pharmaceutica - Drug Research;2024-04-09

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