Tumor-on-a-chip for integrating a 3D tumor microenvironment: chemical and mechanical factors
Author:
Affiliation:
1. Department of Mechanical Engineering
2. Carnegie Mellon University
3. Pittsburgh
4. 15213 US
5. Department of Pharmacology & Chemical Biology
6. University of Pittsburgh Medical Center Hillman Cancer Center
7. Magee Womens Research Institute
Abstract
Tumor progression is significantly influenced by factors such as mechanical force, shear stress, chemotaxis, and hypoxia. Here, we reviewed recent achievements and presented potential directions for tumor-on-a-chip systems in the future.
Funder
Air Force Office of Scientific Research
Office of Naval Research
Pennsylvania Department of Health
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00550A
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