Fluorinated and [18F]fluorinated morphinan based opioid ligands
Author:
Affiliation:
1. Institute of Organoelement Compounds
2. Russian Academy of Sciences
3. Moscow 119991
4. Russia
Abstract
Fluorinated 4,5α-epoxymorphinans, opioid ligands for drug development and PET imaging of opioid receptors using [18F]tracers, are reviewed.
Funder
Ministry of Science and Higher Education of the Russian Federation
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00619J
Reference104 articles.
1. A. van Waarde , A. R.Absalom , A. K. D.Visser and R. A. J. O.Dierckx , in PET and SPECT of Neurobiological Systems , ed. R. A. J. O. Dierckx , et al. , Springer-Verlag , Berlin, Heidelberg , 2014 , ch. 20, pp. 585–623
2. ORL1, a novel member of the opioid receptor family
3. Update 1 of: Over One Hundred Peptide-Activated G Protein-Coupled Receptors Recognize Ligands with Turn Structure
4. Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
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