H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)–cholesteryl conjugates-Reference-Cited by-同舟云学术

H2S-Donating trisulfide linkers confer unexpected biological behaviour to poly(ethylene glycol)–cholesteryl conjugates

Published:2020 Issue:17 Volume:8 Page:3896-3907
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Ercole Francesca¹²³⁴⁵,Li Yuhuan¹²³⁴⁵,Whittaker Michael R.¹²³⁴⁵^ORCID,Davis Thomas P.¹²³⁴⁵^ORCID,Quinn John F.¹²³⁴⁵^ORCID

Affiliation:

1. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology

2. Drug Delivery

3. Disposition and Dynamics Theme, Monash Institute of Pharmaceutical Sciences

4. Monash University

5. Parkville

Abstract

A comprehensive in vitro study into trisulfide-bearing PEG-conjugates was conducted. For these materials the combination of a cholesteryl group and an H₂S donating moiety is required to confer cytoprotective and ROS-mitigating effects.

Funder

Australian Research Council

Monash University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/C9TB02614B

Reference58 articles.

1. Polysulfides in Biology: From Intricate Chemistry to an Astonishing Yet Hidden Biological Activity

2. The Chemistry of Organic Polysulfanes R−Sn−R (n > 2)

3. Synthesis and Structural Properties of the Benzopentathiepins Varacin and Isolissoclinotoxin A

4. Polysulfides as biologically active ingredients of garlic

5. Hydrogen sulfide mediates the vasoactivity of garlic

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Polymeric Nanoparticles for Drug Delivery;Chemical Reviews;2024-04-16

2. Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications;Bioactive Materials;2023-01

3. Cholesterol in drug delivery systems;Cholesterol;2022

4. Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules;Advanced Drug Delivery Reviews;2021-12

5. Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells;Journal of Materials Chemistry B;2021