Do GluN2B subunit containing NMDA receptors tolerate a fluorine atom in the phenylalkyl side chain?-Reference-Cited by-同舟云学术

Do GluN2B subunit containing NMDA receptors tolerate a fluorine atom in the phenylalkyl side chain?

Author:

Shuto Yoshihiro¹²³⁴,Thum Simone⁵⁶⁷,Temme Louisa⁵⁶⁷,Schepmann Dirk⁵⁶⁷,Kitamura Masato¹²³⁴,Wünsch Bernhard⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Nagoya University Chikusa

3. Nagoya 464-8602

4. Japan

5. Institut für Pharmazeutische und Medizinische Chemie der Universität Münster

6. D-48149 Münster

7. Germany

8. Cells-in-Motion Cluster of Excellence (EXC 1003 – CiM)

9. Westfälische Wilhelms-Universität Münster

Abstract

An F-atom in the phenylalkyl side chain of GluN2B antagonists does not affect the affinity towards GluN2B receptors.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference36 articles.

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