Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro-Reference-Cited by-同舟云学术

Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro

Published:2016 Issue:2 Volume:7 Page:805-815
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Cai Xiaxia¹²³⁴⁵,Bao Lei⁶⁷⁴⁵,Ren Jinwei¹²³⁴⁵,Li Yong¹²³⁴⁵,Zhang Zhaofeng¹²³⁴⁵

Affiliation:

1. Department of Nutrition and Food Hygiene

2. School of Public Health

3. Peking University

4. Beijing

5. P. R. China

6. Department of Clinical Nutrition

7. Peking University International Hospital

Abstract

Grape seed procyanidin B2 (GSPB2) was reported to have protective effects on diabetic nephropathy (DN) as a strong antioxidant.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2016/FO/C5FO01062D

Reference45 articles.

1. Podocyte damage damages podocytes: autonomous vicious cycle that drives local spread of glomerular sclerosis

2. Podocyte is the major culprit accounting for the progression of chronic renal disease

3. The podocyte's response to injury: Role in proteinuria and glomerulosclerosis

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