Genome mining methods to discover bioactive natural products-Reference-Cited by-同舟云学术

Genome mining methods to discover bioactive natural products

Published:2021 Issue:11 Volume:38 Page:2100-2129
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Bauman Katherine D.¹^ORCID,Butler Keelie S.²^ORCID,Moore Bradley S.¹³^ORCID,Chekan Jonathan R.²^ORCID

Affiliation:

1. Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, 92093, USA

2. Department of Chemistry and Biochemistry, University of North Carolina Greensboro, Greensboro, NC, 27402, USA

3. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, 92093, USA

Abstract

The continual growth of publicly available genomic databases offers researchers unprecedented bioinformatic opportunities. This review examines different approaches to mining genomic data for the targeted discovery of bioactive natural products.

Funder

National Center for Complementary and Alternative Medicine

National Institutes of Health

University of North Carolina at Greensboro

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NP/D1NP00032B

Reference199 articles.

1. Bioactive Microbial Metabolites

2. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

3. Natural products in drug discovery: advances and opportunities

4. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

Cited by 75 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phylogenomic analysis uncovers an unexpected capacity for the biosynthesis of secondary metabolites in Pseudoalteromonas;European Journal of Medicinal Chemistry;2024-12

2. Diversity and Distribution of Biosynthetic Gene Clusters in the Halophilic Bacteria;2024-08-23

3. Recent advances in genome mining and synthetic biology for discovery and biosynthesis of natural products;Critical Reviews in Biotechnology;2024-08-12

4. Discovery of a terpene synthase synthesizing a nearly non-flexible eunicellane reveals the basis of flexibility;Nature Communications;2024-07-15

5. Discovery of Prenyltransferase-Guided Hydroxyphenylacetic Acid Derivatives from Marine Fungus Penicillium sp. W21C371;Marine Drugs;2024-06-26