Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide–terpenoid hybrids-Reference-Cited by-同舟云学术

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Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide–terpenoid hybrids

Published:2024 Issue:8 Volume:15 Page:3011-3017
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yan Dexiu¹^ORCID,Matsuda Yudai¹^ORCID

Affiliation:

1. Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China

Abstract

Global genome mining resulted in the discovery of an unusual biosynthetic mechanism for fungal meroterpenoids, in which the dimethylallyltryptophan synthase-type prenyltransferase MfmD installs a farnesyl group for subsequent cyclization.

Funder

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC06001B

Reference42 articles.

1. Discovery of microbial natural products by activation of silent biosynthetic gene clusters

2. A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters

3. Genome mining methods to discover bioactive natural products

4. A computational framework to explore large-scale biosynthetic diversity

5. The confluence of big data and evolutionary genome mining for the discovery of natural products

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of fungal onoceroid triterpenoids through domainless enzyme-targeted global genome mining;Nature Communications;2024-05-21

2. Hot off the Press;Natural Product Reports;2024

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