Hypoxia reduces and redirects selenoprotein biosynthesis-Reference-Cited by-同舟云学术

Hypoxia reduces and redirects selenoprotein biosynthesis

Published:2014 Issue:5 Volume:6 Page:1079-1086
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Becker Niels-Peter¹²³,Martitz Janine¹²³,Renko Kostja¹²³,Stoedter Mette¹²³,Hybsier Sandra¹²³,Cramer Thorsten⁴²³,Schomburg Lutz¹²³

Affiliation:

1. Institute for Experimental Endocrinology

2. Charité-Universitätsmedizin Berlin

3. D-13353 Berlin, Germany

4. Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie

Abstract

In hypoxia, selenoprotein biosynthesis becomes redirected in favor of the essentially needed GPX4, thereby preventing the fast activation of cell-death pathways.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MT/C4MT00004H

Reference34 articles.

1. Eukaryotic selenoproteins and selenoproteomes

2. Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

3. Selenium and human health

4. Selenoproteins and Cancer Prevention

5. Selenium and viral virulence

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