A theranostic abscisic acid-based molecular glue-Reference-Cited by-同舟云学术

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A theranostic abscisic acid-based molecular glue

Published:2023 Issue:12 Volume:14 Page:3377-3384
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chen Jing¹^ORCID,Nguyen Huong T. X.²,Yang Ming²,Zeng Fangxun¹,Xu Hang¹,Liang Fu-Sen²,Wang Wei¹^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, 1703 E. Mabel Street, P. O. Box 210207, Tucson, AZ 85721-0207, USA

2. Department of Chemistry, Case Western Reserve University, 2080 Adelbert Road, Cleveland, Ohio 44106, USA

Abstract

A theranostic ABA-based molecular glue, capable of sensing Fe(ii) and triggering the release of ABA and NIR fluorophores, has been developed for spatiotemporal monitoring and manipulating cellular functions.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC06995D

Reference54 articles.

1. The Rise of Molecular Glues

2. Chemically induced proximity in biology and medicine

3. Unifying principles of bifunctional, proximity-inducing small molecules

4. Engineering the ABA Plant Stress Pathway for Regulation of Induced Proximity

5. Rapid and orthogonal logic gating with a gibberellin-induced dimerization system

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