Nickel-catalyzed C-3 direct arylation of pyridinium ions for the synthesis of 1-azafluorenes-Reference-Cited by-同舟云学术

Nickel-catalyzed C-3 direct arylation of pyridinium ions for the synthesis of 1-azafluorenes

Published:2016 Issue:8 Volume:7 Page:5581-5586
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Desrosiers Jean-Nicolas¹²³⁴,Wei Xudong¹²³⁴,Gutierrez Osvaldo⁵⁶⁷⁴^ORCID,Savoie Jolaine¹²³⁴,Qu Bo¹²³⁴,Zeng Xingzhong¹²³⁴,Lee Heewon¹²³⁴,Grinberg Nelu¹²³⁴,Haddad Nizar¹²³⁴,Yee Nathan K.¹²³⁴,Roschangar Frank¹²³⁴,Song Jinhua J.¹²³⁴,Kozlowski Marisa C.⁵⁶⁷⁴,Senanayake Chris H.¹²³⁴

Affiliation:

1. Department of Chemical Development US

2. Boehringer-Ingelheim Pharmaceuticals, Inc.

3. Ridgefield

4. USA

5. Department of Chemistry

6. University of Pennsylvania

7. Philadelphia

Abstract

The reactivity of pyridinium ions was utilized for the first non-precious-metal-catalyzed C-3 direct arylation and was demonstrated by mechanistic studies.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC01457G

Reference52 articles.

1. Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by Cï£¿H Bond Cleavage

2. Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation

3. Palladium-Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by Cï£¿H Bond Activation