Sulfone-Mediated SNAr Reaction as a Powerful Tool for the Synthesis of 4-Quinolinyl Ethers and More—Application to the Synthesis of HCV NS3/4a Protease Inhibitor BI 201420-Reference-Cited by-同舟云学术

Sulfone-Mediated SNAr Reaction as a Powerful Tool for the Synthesis of 4-Quinolinyl Ethers and More—Application to the Synthesis of HCV NS3/4a Protease Inhibitor BI 201420

Published:2020-05-28 Issue:13 Volume:85 Page:8339-8351
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Patel Nitinchandra D.¹^ORCID,Wei Xudong¹,Byrne Denis¹,Narayanan Bikshandarkoil A.¹,Pennino Scott²,Sarvestani Max¹,Saha Anjan¹,Haddad Nizar¹,Kapadia Suresh¹,Lorenz Jon C.¹,DeCroos Philomen¹,Ye Andrew¹,Lee Heewon¹,Grinberg Nelu¹,Hossain Azad¹,Busacca Carl A.¹,Yee Nathan K.¹,Senanayake Chris H.¹

Affiliation:

1. Chemical Development US, Boehringer-Ingelheim Pharmaceuticals Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, Connecticut 06877-0368, United States

2. Material and Analytical Sciences US, Boehringer-Ingelheim Pharmaceuticals Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, Connecticut 06877-0368, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00554

Reference66 articles.

1. The cell biology of hepatitis C virus

2. Cellular and molecular biology of HCV infection and hepatitis

3. Current race in the development of DAAs (direct-acting antivirals) against HCV

4. Current therapy for chronic hepatitis C: The role of direct-acting antivirals

5. Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

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