Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy-Reference-Cited by-同舟云学术

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Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy

Published:2014 Issue:28 Volume:12 Page:5201-5211
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

da Silva A. Filipa F.¹²³,Seixas Raquel S. G. R.¹²³,Silva Artur M. S.¹²³,Coimbra Joana⁴²³,Fernandes Ana C.⁵⁶⁷⁸,Santos Joana P.⁹⁶⁷⁸,Matos António¹⁰¹¹¹²¹³¹⁴,Rino José¹⁵¹⁶¹⁷,Santos Isabel⁵⁶⁷⁸,Marques Fernanda⁵⁶⁷⁸

Affiliation:

1. Departamento de Química-QOPNA

2. Universidade de Aveiro

3. 3810-193 Aveiro, Portugal

4. Laboratório Central de Análises

5. Centro de Ciências e Tecnologias Nucleares

6. Instituto Superior Técnico

7. Universidade de Lisboa

8. , Portugal

9. Laboratório de Engenharia Nuclear

10. Centro de Investigação Interdisciplinar Egas Moniz

11. Caparica, Portugal

12. CESAM-Lisboa

13. Faculdade de Ciências da Universidade de Lisboa

14. 1749-016 Lisboa, Portugal

15. Faculdade de Medicina da Universidade de Lisboa

16. Instituto Medicina Molecular

17. 1649-028 Lisboa, Portugal

Abstract

Acridone derivatives bearing carboranyl moieties as fluorescent probes for boron neutron capture therapy (BNCT) of the glioblastoma.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00644E

Reference48 articles.

1. Glioblastoma and Other Malignant Gliomas

2. Anti-cancer Therapies in High Grade Gliomas

3. Boron Neutron Capture Therapy of Cancer: Current Status and Future Prospects

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