Modulation of the conformational landscape of the PDZ3 domain by perturbation on a distal non-canonical α3 helix: decoding the microscopic mechanism of allostery in the PDZ3 domain-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Modulation of the conformational landscape of the PDZ3 domain by perturbation on a distal non-canonical α3 helix: decoding the microscopic mechanism of allostery in the PDZ3 domain

Published:2024 Issue:31 Volume:26 Page:21249-21259
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Sarkar Subhajit¹,Dhibar Saikat¹,Jana Biman¹^ORCID

Affiliation:

1. School of Chemical Sciences, Indian Association for the Cultivation of Science, Kolkata-700032, India

Abstract

Elucidating allosteric signal transduction in the PDZ3 domain: the pivotal role of the distal α3 helix in modulating conformational landscape and ligand binding affinity.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CP/D4CP01806K

Reference76 articles.

1. Allostery: an illustrated definition for the ‘second secret of life’

2. A Unified View of “How Allostery Works”

3. Emerging maps of allosteric regulation in cellular networks

4. Allosteric Mechanisms of Signal Transduction

5. Molecular Insights into Phosphorylation-Induced Allosteric Conformational Changes in a β₂-Adrenergic Receptor

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP