Use of a novel multicomponent reaction under high pressure for the efficient construction of a new pyridazino[5,4,3-de][1,6]naphthyridine tricyclic system-Reference-Cited by-同舟云学术

Use of a novel multicomponent reaction under high pressure for the efficient construction of a new pyridazino[5,4,3-de][1,6]naphthyridine tricyclic system

Published:2016 Issue:93 Volume:6 Page:90840-90845
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Moustafa Moustafa Sherief¹²³⁴⁵,Al-Mousawi Saleh Mohammed¹²³⁴⁵,Elnagdi Mohamed Hilmy⁶⁷⁵

Affiliation:

1. Chemistry Department

2. Faculty of Science

3. Kuwait University

4. 13060 Safat

5. Kuwait

6. Emeritus Professor of Chemistry

7. Cairo and Kuwait Universities

Abstract

A novel multicomponent reaction between the 2-phenylhydrazono derivative1a, malononitrile and aromatic aldehydes or acetone, carried out under high pressure, was found to generate pyridazino[5,4,3-de][1,6]naphthyridine derivatives9a–hand22.

Funder

Kuwait University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA19535K

Reference38 articles.

1. Thiazolo[4,5-d]pyrimidines as a privileged scaffold in drug discovery

2. Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions

3. 1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

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