Design, synthesis and cytotoxic evaluation of a library of oxadiazole-containing hybrids-Reference-Cited by-同舟云学术

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Design, synthesis and cytotoxic evaluation of a library of oxadiazole-containing hybrids

Published:2021 Issue:47 Volume:11 Page:29741-29751
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Camacho Cristián M.¹,Pizzio Marianela G.¹,Roces David L.¹,Boggián Dora B.¹,Mata Ernesto G.¹^ORCID,Bellizzi Yanina²,Barrionuevo Elizabeth²,Blank Viviana C.²^ORCID,Roguin Leonor P.²^ORCID

Affiliation:

1. Instituto de Química Rosario (CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina

2. Instituto de Química y Fisicoquímica Biológicas (UBA – CONICET), Facultad de Farmacia y Bioquímica, UBA, Junín 956, C1113AAD Buenos Aires, Argentina

Abstract

Synthesized hybrids of 1,2,4-oxadiazole and 1,3,4-oxadiazole connecting a penicillin and aliphatic amino acids displayed a high degree of cytotoxic selectivity.

Funder

Fondo para la Investigación Científica y Tecnológica

Consejo Nacional de Investigaciones Científicas y Técnicas

Universidad de Buenos Aires

Universidad Nacional de Rosario

Agencia Santafesina de Ciencia, Tecnología e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05602F

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5. T.Eicher , S.Hauptmann and A.Speicher , The Chemistry of Heterocycles , Wiley-VCH Verlag GmbH & Co , Weinheim , 2nd edn, 2003

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