Design, synthesis, biological evaluation and molecular docking of novel dabigatran derivatives as potential thrombin inhibitors
Author:
Affiliation:
1. School of Chemical and Environmental Engineering
2. Shanghai Institute of Technology
3. Shanghai
4. P. R. China
Abstract
A series of dabigatran derivatives were designed and synthesized to discover effective thrombin inhibitors.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA01828E
Reference23 articles.
1. Antithrombotic drugs market
2. Triggers, targets and treatments for thrombosis
3. Fibrinogen and fibrin structure and functions
4. Mechanisms of platelet activation by thrombin: A short history
5. Direct Thrombin Inhibitors
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