MRI and luminescence detection of Zn2+ with a lanthanide complex–zinc finger peptide conjugate

Author:

Isaac Manon12345,Pallier Agnès678910,Szeremeta Frédéric678910,Bayle Pierre-Alain13111213,Barantin Laurent1415161710,Bonnet Célia S.678910ORCID,Sénèque Olivier12345

Affiliation:

1. Univ. Grenoble Alpes

2. CNRS

3. CEA

4. BIG

5. LCBM (UMR 5249)

6. Centre de Biophysique Moléculaire

7. UPR CNRS 4301

8. Université d'Orléans

9. F-45071 Orléans

10. France

11. INAC

12. MEM

13. F-38000 Grenoble

14. UMR 1253

15. iBrain

16. Université de Tours

17. Tours

Abstract

A zinc finger peptide provides an excellent scaffold for the design of lanthanide-based luminescent and MRI Zn2+-responsive probes

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference24 articles.

1. Imaging free zinc levels in vivo – What can be learned?

2. Zinc in Specialized Secretory Tissues: Roles in the Pancreas, Prostate, and Mammary Gland

3. Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

4. C. S. Bonnet , L.Tei , M.Botta and É.Tóth , in The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging , ed. A. Merbach , L. Helm and É. Tóth , John Wiley & Sons, Ltd , 2013 , pp. 343–385

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