Enhancing the ROS generation ability of a rhodamine-decorated iridium(iii) complex by ligand regulation for endoplasmic reticulum-targeted photodynamic therapy

Author:

Zhou Lihua12345,Wei Fangfang6789,Xiang Jingjing12345,Li Hongfeng12345,Li Chunbin12345,Zhang Pengfei12345ORCID,Liu Chuangjun678910,Gong Ping12345,Cai Lintao12345ORCID,Wong Keith Man-Chung6789ORCID

Affiliation:

1. Guangdong Key Laboratory of Nanomedicine

2. Shenzhen Engineering Laboratory of Nanomedicine and Nanoformulations

3. CAS Key Lab for Health Informatics

4. Shenzhen Institutes of Advanced Technology

5. Chinese Academy of Sciences

6. Department of Chemistry

7. Southern University of Science and Technology

8. Shenzhen 518055

9. P. R. China

10. College of Chemistry and Pharmaceutical Engineering

Abstract

A design strategy for boosting the ROS generation of rhodamine-decorated cyclometallated iridium(iii) complexes by ligand regulation for endoplasmic reticulum-targeted precise photodynamic therapy.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Science, Technology and Innovation Commission of Shenzhen Municipality

China Postdoctoral Science Foundation

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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