Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting-Reference-Cited by-同舟云学术

Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting

Published:2011-01-05 Issue:64 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Murakami Mami¹,Cabral Horacio¹²,Matsumoto Yu³,Wu Shourong³,Kano Mitsunobu R.⁴,Yamori Takao⁵,Nishiyama Nobuhiro²³,Kataoka Kazunori¹²³⁶

Affiliation:

1. Department of Bioengineering, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

2. Center for NanoBio Integration, University of Tokyo, Tokyo 113-8656, Japan.

3. Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.

4. Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.

5. Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo 135-8550, Japan.

6. Department of Materials Engineering, Graduate School of Engineering, University of Tokyo, Tokyo 113-8656, Japan.

Abstract

Polymeric micelles containing a chemotherapeutic drug carry it adjacent to the DNA target in tumor cells, enhancing the drug potency.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

1. Cancer Statistics, 2009

2. Drug Delivery Systems: Entering the Mainstream

3. Cancer nanotechnology: opportunities and challenges

4. Recent advances with liposomes as pharmaceutical carriers

5. The dawning era of polymer therapeutics

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