Cellular heterogeneity identified by single-cell alkaline phosphatase (ALP) via a SERRS-microfluidic droplet platform

Author:

Sun Dan12345,Cao Fanghao12345,Cong Lili12345,Xu Weiqing12345ORCID,Chen Qidan67385,Shi Wei9345,Xu Shuping12345ORCID

Affiliation:

1. State Key Laboratory of Supramolecular Structure and Materials

2. Institute of Theoretical Chemistry

3. Jilin University

4. Changchun 130012

5. PR China

6. School of Chemical Engineering and New Energy Materials

7. Zhuhai College

8. Zhuhai 519041

9. Key Lab for Molecular Enzymology & Engineering of Ministry of Education

Abstract

We proposed an ultrasensitive method for studying low abundance ALP secreted by individual cell using the microfluidic droplet-based SERRS technique.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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