A novel square-planar Pt(ii) complex as a monomeric and dimeric G-quadruplex DNA binder-Reference-Cited by-同舟云学术

A novel square-planar Pt(ii) complex as a monomeric and dimeric G-quadruplex DNA binder

Published:2018 Issue:41 Volume:8 Page:23257-23261
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhou Chun-Qiong¹²³⁴⁵^ORCID,Li Zi-Qi¹²³⁴⁵,Liao Ting-Cong¹²³⁴⁵,Ma Tian-Zhu¹²³⁴⁵,Chen Shuo-Bin²⁶⁷⁵^ORCID,Liang Yuan-Yuan¹²³⁴⁵

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Screening

2. School of Pharmaceutical Sciences

3. Southern Medical University

4. Guangzhou 510515

5. China

6. Sun Yat-sen University

7. Guangzhou 51006

Abstract

A phenanthroimidazole ethylenediamine Pt(ii) complex with coumarin derivative (1) showed high binding properties and thermal stabilization for dimeric quadruplexes G2T1.

Funder

National Natural Science Foundation of China

Guangdong Science and Technology Department

Southern Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03606C

Reference25 articles.

1. Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound

2. Quadruplex Nucleic Acids as Novel Therapeutic Targets

3. Quadruplex nucleic acids as targets for anticancer therapeutics

4. High-throughput sequencing of DNA G-quadruplex structures in the human genome

5. The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium

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