A core-satellite micellar system against primary tumors and their lymphatic metastasis through modulation of fatty acid metabolism blockade and tumor-associated macrophages-Reference-Cited by-同舟云学术

A core-satellite micellar system against primary tumors and their lymphatic metastasis through modulation of fatty acid metabolism blockade and tumor-associated macrophages

Published:2023 Issue:18 Volume:15 Page:8320-8336
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

He Xuan¹,Deng Tao¹,Li Jiaxin¹,Guo Rong¹,Wang Yashi¹,Li Ting¹,Zang Shuya¹,Li Jiaxin¹,Zhang Ling²,Li Man¹,He Qin¹^ORCID

Affiliation:

1. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Med-X Center for Materials, Sichuan University, China

2. College of Polymer Science and Engineering, Sichuan University, China

Abstract

A core-satellite micellar system, PCL/PTX@DSPE/ET, can simultaneously act on primary tumors and their lymphatic metastasis, including TIME modulation at the tumor site and metabolic inhibition of FAO-adapted tumor cells in TDLNs.

Funder

Sichuan Province Science and Technology Support Program

Sichuan University

China Agricultural Research System

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR04693H

Reference62 articles.