A comparative analysis of 3D printed scaffolds consisting of poly(lactic-co-glycolic) acid and different bioactive mineral fillers: aspects of degradation and cytocompatibility

Author:

Ahlfeld Tilman1ORCID,Lode Anja1,Placht Anna-Maria1,Fecht Tatjana2,Wolfram Tobias2,Grom Stefanie2,Hoess Andreas3ORCID,Vater Corina1,Bräuer Christian4ORCID,Heinemann Sascha3,Lauer Günter4,Reinauer Frank2,Gelinsky Michael1ORCID

Affiliation:

1. Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2. Karl Leibinger Medizintechnik GmbH & Co. KG (KLS Martin Group), Germany

3. INNOTERE GmbH, Radebeul, Germany

4. Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

Abstract

Leveraging 3D-printable PLGA composites with mineral fillers, biomaterial-based bone therapies become clinically relevant. Herein, long-termin vitroexperiments were conducted to characterize degradability and evidence cytocompatibility.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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