Efficient synthesis of tetrasubstituted 2,3-allenoates and preliminary studies on bioactivities-Reference-Cited by-同舟云学术

Efficient synthesis of tetrasubstituted 2,3-allenoates and preliminary studies on bioactivities

Published:2019 Issue:3 Volume:6 Page:304-308
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yao Yuan¹²³⁴⁵,Zhu Guirong¹²³⁴⁵,Chen Qin¹²³⁴⁵,Qian Hui¹²³⁴⁵,Ma Shengming¹²³⁴⁵^ORCID

Affiliation:

1. Research Center for Molecular Recognition and Synthesis

2. Department of Chemistry

3. Fudan University

4. Shanghai 200433

5. P. R. China

Abstract

A general and highly efficient straightforward protocol for the preparation of tetrasubstituted 2,3-allenoates through a palladium-catalyzed coupling reaction of 3-alkoxycarbonyl propargylic carbonates and boronic acids with commercially available tri(o-tolyl)phosphine as a ligand has been developed.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C8QO01202D

Reference85 articles.

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2. Palladium-Catalyzed Reactions of Allenes

3. Synthesis and Reactions of Allylic, Allenic, Vinylic, and Arylmetal Reagents from Halides and Esters via Transient Organopalladium Intermediates