Sulfonamide vs. sulfonimide: tautomerism and electronic structure analysis of N-heterocyclic arenesulfonamides
Author:
Affiliation:
1. Department of Medicinal Chemistry
2. National Institute of Pharmaceutical Education and Research
3. Punjab – 160 062
4. India
5. Department of Chemistry
6. Indian Institute of Technology (IIT) Ropar
7. Roopnagar – 140 001
Abstract
Experimental and computational studies suggest a preference toward the sulfonimide tautomer in N-heterocyclic arenesulfonamide.
Funder
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ01353A
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5. Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of N-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ETA Selective Antagonist
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