Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans
Author:
Affiliation:
1. Department of Biochemistry
2. University of Geneva
3. CH-1205 Geneva
4. Switzerland
5. National Centre of Competence in Research (NCCR) “Chemical Biology”
6. Department of Chemistry
7. University of Fribourg
8. CH-1700 Fribourg
Abstract
Nematode-specific iso-branched sphingoid base synthesis: drug-target against parasites and genetic model system for human diseases.
Funder
European Molecular Biology Organization
Swiss National Science Foundation
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC04831E
Reference40 articles.
1. Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols
2. Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster
3. Distribution and Functions of Sterols and Sphingolipids
4. The glycosylceramides of the nematodeCaenorhabditis elegans contain an unusual, branched-chain sphingoid base
5. Isolation and structural analysis of three neutral glycosphingolipids from a mixed population of Caenorhabditis elegans (Nematoda: Rhabditida)
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