Functional lipids based on [12]aneN3 and naphthalimide as efficient non-viral gene vectors

Author:

Gao Yong-Guang12345,Alam Uzair12345,Tang Quan12345,Shi You-Di12345,Zhang Ying12345,Wang Ruibing678910,Lu Zhong-Lin12345

Affiliation:

1. Key Laboratory of Theoretical and Computational Photochemistry

2. Ministry of Education

3. College of Chemistry

4. Beijing Normal University

5. Beijing 100875

6. State Key Laboratory of Quality Research in Chinese Medicine

7. Institute of Chinese Medical Sciences

8. University of Macau

9. Taipa

10. China

Abstract

Small organic non-viral gene vectors with the structural combinations of (aliphatic chain)–naphthalimide–[12]aneN3 (11a, b) and naphthalimide–(aliphatic chain)–[12]aneN3 (12a–c) were synthesized and fully characterized.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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