Biological activity of dendrimer–methylglyoxal complexes for improved therapeutic efficacy against malignant cells

Author:

Ghosh Srabanti1234,Chakraborty Prabal5674,Chakrabarti Adrita8234,Ghosh Manosij91011124,Mandal Amit13234,Saha Partha5674,Mukherjee Anita91011124,Acharya Somobrata1234,Ray Manju823414

Affiliation:

1. Centre for Advanced Materials

2. Indian Association for the Cultivation of Science

3. Kolkata-700032

4. India

5. Crystallography and Molecular Biology Division

6. Saha Institute of Nuclear Physics

7. Kolkata-700064

8. Biological Chemistry

9. Centre of Advanced Study

10. Department of Botany

11. University of Calcutta

12. Kolkata-700019

13. Polymer Science Unit

14. Division of Molecular Medicine

Abstract

A facile strategy to synthesize polymer based conjugation of methylglyoxal which demonstrated inhibition against malignant cells with desired selectivity can revolutionize the cancer treatment via minimizing the human health risks.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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