In silico design and in vitro assessment of anti-Helicobacter pylori compounds as potential small-molecule arginase inhibitors

Author:

Fiori-Duarte Ana Thereza,de Oliveira Guarnieri João Paulo,de Oliveira Borlot Jessica Rodrigues Pereira,Lancellotti Marcelo,Rodrigues Ricardo Pereira,Kitagawa Rodrigo Rezende,Kawano Daniel FábioORCID

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Reference82 articles.

1. World Health Organization (WHO) (2017) WHO publishes list of bacteria for which new antibiotics are urgently needed. http://www.who.int/mediacentre/news/releases/2017/bacteria-antibiotics-needed/en/. Accessed 1 May 2020

2. Bray F, Ferlay J, Soerjomataram I et al (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68:394–424. https://doi.org/10.3322/caac.21492

3. Howden CW, Chey WD, Vakil NB (2014) Clinical rationale for confirmation testing after treatment of Helicobacter pylori infection: implications of rising antibiotic resistance. Gastroenterol Hepatol 10:1–19

4. The Global Cancer Observatory (2020) International agency for research on cancer—IARC. https://gco.iarc.fr/today/data/factsheets/cancers/7-Stomach-fact-sheet.pdf. Accessed 31 Aug 2021

5. Polk DB, Peek RM (2010) Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer 10:403–414. https://doi.org/10.1038/nrc2857

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