Similar color analysis based on deep learning (SCAD) for multiplex digital PCR <i>via</i> a single fluorescent channel-Reference-Cited by-同舟云学术

Similar color analysis based on deep learning (SCAD) for multiplex digital PCR via a single fluorescent channel

Published:2022 Issue:20 Volume:22 Page:3837-3847
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Cao Chaoyu¹²,You Minli¹²,Tong Haoyang¹²,Xue Zhenrui²³,Liu Chang¹²,He Wanghong²⁴,Peng Ping²³,Yao Chunyan³,Li Ang⁴,Xu Xiayu¹²,Xu Feng¹²^ORCID

Affiliation:

1. The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China

2. Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, P.R. China

3. Department of Transfusion Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, P.R. China

4. Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710049, P.R. China

Abstract

We proposed an explainable deep learning-based method to classify similar fluorescence colors for multiplex digital PCR in a single fluorescent channel.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Fundamental Research Funds for the Central Universities

China Postdoctoral Science Foundation

Key Research and Development Projects of Shaanxi Province

Natural Science Foundation of Shaanxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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