Design and synthesis of new 4-(2-nitrophenoxy)benzamide derivatives as potential antiviral agents: molecular modeling and in vitro antiviral screening

Author:

Abdallah Abdallah E.1,Alesawy Mohamed S.1ORCID,Eissa Sally I.23,El-Fakharany Esmail M.4,Kalaba Mohamed H.5,Sharaf Mohamed H.5,Abo Shama Noura M.6,Mahmoud Sara H.6,Mostafa Ahmed6ORCID,Al-Karmalawy Ahmed A.7ORCID,Elkady Hazem1ORCID

Affiliation:

1. Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11884, Egypt

3. Faculty of Pharmacy Al-Maareffa University for Science and Technology, Riyadh, Kingdom of Saudi Arabia

4. Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, Egypt

5. Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Egypt

6. Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt

7. Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta 34518, Egypt

Abstract

Novel benzamide derivatives as anti adenovirus, HSV-1, coxsackievirus, and SARS-CoV-2: in vitro and in silico study.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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