Advancements and applications of loop‐mediated isothermal amplification (LAMP) technology in the detection of viral diseases in fruit crops

Author:

Luo Liting1,Khan Mehran1,Chen Songshu1,Wang Fen2,Xie Xin1ORCID

Affiliation:

1. Key Laboratory of Agricultural Microbiology, College of Agriculture Guizhou University Guiyang China

2. School of Biological Science and Agriculture Qiannan Normal University for Nationalities Duyun China

Abstract

AbstractEarly diagnosis has a pivotal role in the effective control and prevention of disease in fruit crops. Loop‐mediated isothermal amplification (LAMP) has emerged as a prominent modality for disease diagnosis owing to its rapid detection, heightened sensitivity, exceptional specificity and easy operational procedures. The advent of LAMP‐coupled CRISPR‐Cas12, multiplex LAMP (mLAMP) and digital LAMP (dLAMP) has contributed to a paradigm shift in the field and increased the applicability of LAMP technology in viral disease detection. Such advancements have further extended the reach and efficacy of LAMP methodologies in diagnostic research. Here, we review LAMP detection technology application to identify viral diseases in fruits (e.g., apple, passion fruit, banana and citrus) and summarize current developments in LAMP technology and its future prospects, which could enhance its application in the detection of fruit viral diseases.

Publisher

Wiley

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