Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions-Reference-Cited by-同舟云学术

Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions

Published:2016 Issue:91 Volume:52 Page:13353-13356
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Okoromoba Otome E.¹²³⁴,Li Zhou¹²³⁴,Robertson Nicole¹²³⁴,Mashuta Mark S.¹²³⁴,Couto Uenifer R.⁵⁶⁷⁸,Tormena Cláudio F.⁵⁶⁷⁸^ORCID,Xu Bo⁹¹⁰¹¹,Hammond Gerald B.¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of Louisville

3. Louisville

4. USA

5. Institute of Chemistry

6. University of Campinas

7. São Paulo 13083-970

8. Brazil

9. College of Chemistry, Chemical Engineering and Biotechnology, Donghua University

10. Shanghai 201620

11. China

Abstract

DMPU–HF demonstrates good reactivity and regioselectivity in conversion of aziridines into biologically important β-fluoroamines. The stereochemistry of aziridine-opening was found to be depend greatly on substitution pattern.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07855A

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4. Regioselectivity in the ring opening of non-activated aziridines

5. Palladium-catalysed C–H activation of aliphatic amines to give strained nitrogen heterocycles

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