Moving into the red – a near infra-red optical probe for analysis of human neutrophil elastase in activated neutrophils and neutrophil extracellular traps-Reference-Cited by-同舟云学术

Moving into the red – a near infra-red optical probe for analysis of human neutrophil elastase in activated neutrophils and neutrophil extracellular traps

Published:2023 Issue:78 Volume:59 Page:11660-11663
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Rodriguez-Rios M.¹^ORCID,Rinaldi G.²,Megia-Fernandez A.¹³,Lilienkampf A.¹^ORCID,Robb C. T.²,Rossi A. G.²,Bradley M.⁴^ORCID

Affiliation:

1. EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, EH9 3FJ Edinburgh, UK

2. University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh BioQuarter, Edinburgh EH16 4TJ, UK

3. Organic Chemistry Department, Faculty of Sciences, University of Granada, Avda. Fuente Nueva S/N, 18071, Spain

4. Precision Healthcare University Research Institute, Queen Mary University of London, Empire House, 67-75 New Road, London E1 1HH, UK

Abstract

A tri-branched, FRET-based probe for the detection of hNE was synthesised with emission in the NIR region of the spectrum, where endogenous biomolecules have decreased absorbance, and minimal autofluorescence.

Funder

Medical Research Foundation

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC03634K

Reference33 articles.

1. Neutrophil recruitment and function in health and inflammation

2. Mechanisms of Degranulation in Neutrophils

3. Neutrophil Extracellular Traps Kill Bacteria

4. A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics

5. NETosis and Neutrophil Extracellular Traps in COVID-19: Immunothrombosis and Beyond

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