Epigenetic toxicity of trichloroethylene: a single-molecule perspective-Reference-Cited by-同舟云学术

Epigenetic toxicity of trichloroethylene: a single-molecule perspective

Published:2016 Issue:2 Volume:5 Page:641-650
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Cui Yi¹²³⁴⁵,Choudhury Samrat Roy¹²³⁴⁵,Irudayaraj Joseph¹²³⁴⁵

Affiliation:

1. Department of Agricultural and Biological Engineering

2. Bindley Bioscience Center

3. Purdue Center for Cancer Research

4. Purdue University

5. West Lafayette

Abstract

The volatile, water soluble trichloroethylene (TCE) is a hazardous industrial waste and could lead to various health problems through disrupting the interaction between DNA and epigenetic enzymes.

Funder

W.M. Keck Foundation

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/TX/C5TX00454C

Reference37 articles.

1. EPA, Toxicological review of trichloroethylene. CAS No 79-01-6, http://www2.epa.gov/iris

2. Agency for toxic substances and disease registry (ATSDR): Toxicological profile for trichloroethylene, http://www.atsdr.cdc.gov/toxprofiles/tp.asp?id=173&tid=30

3. C. A. Cooney , in Trichloroethylene: Toxicity and Health Risks, Springer, 2014, pp. 185–208

4. The Quantitatively Important Relationship between Homocysteine Metabolism and Glutathione Synthesis by the Transsulfuration Pathway and Its Regulation by Redox Changes

5. A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis

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