A peptide–drug hydrogel to enhance the anti-cancer activity of chlorambucil-Reference-Cited by-同舟云学术

A peptide–drug hydrogel to enhance the anti-cancer activity of chlorambucil

Published:2020 Issue:20 Volume:8 Page:5638-5646
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Guo Qingxiang¹²³⁴⁵,Liu Yifan⁶⁷⁸⁵,Mu Ganen¹²³⁴⁵,Yang Lijun¹²³⁴⁵,Wang Wei⁶⁷⁸⁵^ORCID,Liu Jinjian¹²³⁴⁵^ORCID,Liu Jianfeng¹²³⁴⁵^ORCID

Affiliation:

1. Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine

2. Institute of Radiation Medicine

3. Chinese Academy of Medical Sciences & Peking Union Medical College

4. Tianjin

5. China

6. College of Materials Science and Engineering

7. Qingdao University of Science and Technology

8. Qingdao

Abstract

The CRB–FFF–cyclen could transform into a hydrogel via a heating–cooling process. The resulting hydrogel could be protonated in a tumor environment, which is beneficial for cellular uptake and anti-tumor activity.

Funder

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China

China Postdoctoral Science Foundation

Chinese Academy of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM01001D

Reference46 articles.

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5. Molecular afterglow imaging with bright, biodegradable polymer nanoparticles

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