Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures-Reference-Cited by-同舟云学术

Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures

Published:2022 Issue:2 Volume:22 Page:225-239
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Dornhof Johannes¹^ORCID,Kieninger Jochen¹^ORCID,Muralidharan Harshini²,Maurer Jochen²,Urban Gerald A.¹,Weltin Andreas¹^ORCID

Affiliation:

1. Laboratory for Sensors, IMTEK – Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 103, 79110 Freiburg, Germany

2. Molecular Gynecology, Clinic for Gynecology and Obstetrics, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany

Abstract

An organ-on-chip platform equipped with microsensors for long-term microfluidic cultivation and metabolic monitoring (O2, Glu, Lac) of 3D tumour organoid cultures grown from patient-derived single cancer stem cells.

Funder

Baden-Württemberg Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC00689D

Reference58 articles.

1. Personalised organs-on-chips: functional testing for precision medicine

2. Microfluidic 3D cell culture: from tools to tissue models

3. KDM4 Inhibition Targets Breast Cancer Stem–like Cells

4. Organs-on-chips: into the next decade

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