DFT and AFIR study on the copper(i)-catalyzed mechanism of 5-enamine-trisubstituted-1,2,3-triazole synthesis via C–N cross-coupling and the origin of ring-opening of 2H-azirines-Reference-Cited by-同舟云学术

DFT and AFIR study on the copper(i)-catalyzed mechanism of 5-enamine-trisubstituted-1,2,3-triazole synthesis via C–N cross-coupling and the origin of ring-opening of 2H-azirines

Published:2021 Issue:5 Volume:11 Page:2744-2755
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yu Fan¹²³⁴⁵,Zhou Zhaoman¹²³⁴⁵,Song Jiajia¹²³⁴⁵,Zhao Yanying¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province

3. Zhejiang Sci-Tech University

4. Hangzhou 310018

5. China

Abstract

The Cu(i)-catalyzed mechanism of 5-enamined-functionalized fully substituted 1,2,3-triazole synthesis was rationalized by interrupted copper(i)-catalyzed terminal alkynes and organic azides click reaction (CuAAC).

Funder

National Natural Science Foundation of China

Zhejiang Sci-Tech University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA07498E

Reference67 articles.

1. Cu(I)-Catalyzed Huisgen Azide−Alkyne 1,3-Dipolar Cycloaddition Reaction in Nucleoside, Nucleotide, and Oligonucleotide Chemistry

2. Heterologous Prime-Boost Enhances the Antitumor Immune Response Elicited by Plant-Virus-Based Cancer Vaccine