An activatable fluorescent prodrug of paclitaxel and BODIPY-Reference-Cited by-同舟云学术

An activatable fluorescent prodrug of paclitaxel and BODIPY

Published:2021 Issue:9 Volume:9 Page:2308-2313
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Xia Jinxiu¹²³⁴⁵,Pei Qing⁶⁷⁸⁹⁵,Zheng Min¹²³⁴⁵^ORCID,Xie Zhigang⁶⁷⁸⁹⁵^ORCID

Affiliation:

1. School of Chemistry and Life Science

2. Advanced Institute of Materials Science

3. Changchun University of Technology

4. 2055 Yanan Street

5. Changchun

6. State Key Laboratory of Polymer Physics and Chemistry

7. Changchun Institute of Applied Chemistry

8. Chinese Academy of Sciences

9. 5625 Renmin Street

Abstract

A redox-activated paclitaxel prodrug (PTX-S-BDP) was synthesized. PTX-S-BDP NPs were fabricated by the coassembly of PTX-S-BDP with F-127, which can release PTX under redox conditions and exhibit superior cellular imaging and selectivity to cancer cells.

Funder

National Natural Science Foundation of China

Education Department of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D0TB02510K

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