Computational methods directed towards drug repurposing for COVID-19: advantages and limitations

Author:

Sharma Prem Prakash1,Bansal Meenakshi1ORCID,Sethi Aaftaab2,Poonam 3ORCID,Pena Lindomar4,Goel Vijay Kumar5,Grishina Maria6,Chaturvedi Shubhra7,Kumar Dhruv8,Rathi Brijesh1ORCID

Affiliation:

1. Laboratory For Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, 110007, India

2. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India

3. Department of Chemistry, Miranda House, University of Delhi, Delhi, 110007 India

4. Department of Virology, Aggeu Magalhaes, Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, Pernambuco, Brazil

5. School of Physical Sciences, Jawaharlal Nehru University, New Delhi, 110067, India

6. South Ural State University, Laboratory of Computational Modelling of Drugs, Pr. Lenina, 76 454080, Russia

7. Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, New Delhi 110054, India

8. Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, Noida 201313, India

Abstract

Different kind of methods utilized in expediting drug repurposing.

Funder

Russian Foundation for Basic Research

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference79 articles.

1. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018

2. M.Placchi and R. J.Phillips , The Benefits and Pitfalls of Repurposing Drugs , https://oliver-dev.s3.amazonaws.com/2018/11/07/21/59/08/240/Benefits%20and%20Pitfalls%20of%20Repurposing%20Drugs.pdf , accessed Febuary 26, 2021

3. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

4. Identification of SARS-CoV-2 entry inhibitors among already approved drugs

5. S.Naylor and J. M.Schonfeld , Therapeutic Drug Repurposing, Repositioning and Rescue Part I: Overview , https://www.ddw-online.com/therapeutic-drug-repurposing-repositioning-and-rescue-part-i-overview-1463-201412/ , accessed March15, 2021

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3